Targeting dendritic cells with nano-particulate PLGA cancer vaccine formulations.

  title={Targeting dendritic cells with nano-particulate PLGA cancer vaccine formulations.},
  author={Samar Ismail Hamdy and Azita Haddadi and R. T. W. Hung and Afsaneh Lavasanifar},
  journal={Advanced drug delivery reviews},
  volume={63 10-11},
Development of safe and effective cancer vaccine formulation is a primary focus in the field of cancer immunotherapy. The recognition of the crucial role of dendritic cells (DCs) in initiating anti-tumor immunity has led to the development of several strategies that target vaccine antigens to DCs as an attempt for developing potent, specific and lasting anti-tumor T cell responses. The main objective of this review is to provide an overview on the application of poly (d,l-lactic-co-glycolic… CONTINUE READING
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