Targeting cocaine versus heroin memories: divergent roles within ventromedial prefrontal cortex.

  title={Targeting cocaine versus heroin memories: divergent roles within ventromedial prefrontal cortex.},
  author={J. Peters and T. Pattij and Taco J. de Vries},
  journal={Trends in pharmacological sciences},
  volume={34 12},
  • J. Peters, T. Pattij, Taco J. de Vries
  • Published 2013
  • Medicine, Psychology
  • Trends in pharmacological sciences
  • In the search for novel treatments for addiction, most research has been propelled by the hope for a 'magic bullet' that would cure all forms of addiction. More recently, the field has started to appreciate the differences between psychostimulants versus opiates. Recent data suggest that the ventromedial prefrontal cortex (vmPFC) may fundamentally serve different roles in cocaine versus heroin addiction: acting as a neural OFF switch for cocaine seeking, but an ON switch for heroin seeking. We… CONTINUE READING
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