Targeting cells with single vectors using multiple-feature Boolean logic

Abstract

Precisely defining the roles of specific cell types is an intriguing frontier in the study of intact biological systems and has stimulated the rapid development of genetically encoded tools for observation and control. However, targeting these tools with adequate specificity remains challenging: most cell types are best defined by the intersection of two or… (More)
DOI: 10.1038/nmeth.2996

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