Targeting autophagy promote the 5-fluorouracil induced apoptosis in human colon cancer cells

Colon cancer is a leading cause of cancer-related death in developed countries. Although 5-fluorouracil (5FU) has traditionally been studied for its potential to induce apoptosis, its clinical use had been greatly limited as a result of the development of drug resistance in patients. Besides the medicines that could induce apoptosis in cancer cells, several… CONTINUE READING