Targeting autoimmune diabetes with gene therapy.

  title={Targeting autoimmune diabetes with gene therapy.},
  author={Nick Giannoukakis and W A Rudert and P. D. Robbins and Matteo Trucco},
  volume={48 11},
The autoimmune nature of insulin-dependent, or type 1, diabetes targets the beta-cells of the pancreas for destruction and results in a lifelong commitment to insulin replacement therapy. Although the number of formulations and dosing of insulin have become more sophisticated and more efficient in recent years, insulin therapy alone is unable to prevent nephropathy, retinopathy, or vascular and heart disease, which still occur in a large number of patients. Different approaches have been… CONTINUE READING


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