Targeting a Long Noncoding RNA in Breast Cancer.

  title={Targeting a Long Noncoding RNA in Breast Cancer.},
  author={Joshua T. Mendell},
  journal={The New England journal of medicine},
  volume={374 23},
The central dogma of molecular biology posits that genes are transcribed into messenger RNA (mRNA), which is then translated into proteins, which, in turn, are ultimately responsible for all cellular functions. Yet recent research has revealed that RNAs that do not encode proteins — known as noncoding RNAs — play important roles in normal physiological processes and can contribute to human diseases such as cancer.1 In fact, only approximately 1.5% of the roughly 3 billion base pairs of DNA in… CONTINUE READING
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