Targeting Wnt signaling to improve wound healing after myocardial infarction.

Abstract

Myocardial infarction is one of the major causes of left ventricular dilatation, frequently leading to heart failure. In the last decade, the wound healing process that takes place in the infarct area after infarction has been recognized as a novel therapeutic target to attenuate left ventricular dilatation and preserve an adequate cardiac function. In this chapter, we discuss the role of Wnt signaling in the wound healing process after infarction, with a specific focus on its modulating effect on myofibroblast characteristics.

DOI: 10.1007/978-1-62703-505-7_21

Cite this paper

@article{Daskalopoulos2013TargetingWS, title={Targeting Wnt signaling to improve wound healing after myocardial infarction.}, author={Evangelos P. Daskalopoulos and Ben J. A. Janssen and W. Matthijs Blankesteijn}, journal={Methods in molecular biology}, year={2013}, volume={1037}, pages={355-80} }