Targeting Tyrosine Kinases and Autophagy in Prostate Cancer

@inproceedings{Kung2011TargetingTK,
  title={Targeting Tyrosine Kinases and Autophagy in Prostate Cancer},
  author={Hsing-Jien Kung},
  booktitle={Hormones & cancer},
  year={2011}
}
Tyrosine kinases play significant roles in tumor progression and therapy resistance. Inhibitors of tyrosine kinases are on the forefront of targeted therapy. For prostate cancer, tyrosine kinases play an additional role in the development of castration-resistant disease state, the most troubling aspect of prostate cancinogenesis which presently defies any effective treatment. Among the 30 or so tyrosine kinases expressed in a typical prostate cancer cell, nearly one third of them have been… CONTINUE READING

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