Targeting Survivin in Cancer: Novel Drug Development Approaches

@inproceedings{Groner2013TargetingSI,
  title={Targeting Survivin in Cancer: Novel Drug Development Approaches},
  author={Bernd Groner and Astrid Weiss},
  booktitle={BioDrugs},
  year={2013}
}
Survivin is a well-established target in experimental cancer therapy. The molecule is over-expressed in most human tumors, but hardly detectable in normal tissues. Multiple functions in different subcellular compartments have been assigned. It participates in the control of cell division, apoptosis, the cellular stress response, and also in the regulation of cell migration and metastasis. Survivin expression has been recognized as a biomarker: high expression indicates an unfavorable prognosis… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 2 times over the past 90 days. VIEW TWEETS

From This Paper

Figures, tables, results, connections, and topics extracted from this paper.
29 Extracted Citations
108 Extracted References
Similar Papers

Citing Papers

Publications influenced by this paper.
Showing 1-10 of 29 extracted citations

Referenced Papers

Publications referenced by this paper.
Showing 1-10 of 108 references

Similar Papers

Loading similar papers…