Targeting SRC and tubulin in mucinous ovarian carcinoma.

Abstract

PURPOSE To investigate the antitumor effects of targeting Src and tubulin in mucinous ovarian carcinoma. EXPERIMENTAL DESIGN The in vitro and in vivo effects and molecular mechanisms of KX-01, which inhibits Src pathway and tubulin polymerization, were examined in mucinous ovarian cancer models. RESULTS In vitro studies using RMUG-S and RMUG-L cell… (More)
DOI: 10.1158/1078-0432.CCR-13-1305

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