Targeting Nuclear Receptors with Marine Natural Products

@inproceedings{Yang2014TargetingNR,
  title={Targeting Nuclear Receptors with Marine Natural Products},
  author={Chunyan Yang and Qian-rong Li and Yong Li},
  booktitle={Marine drugs},
  year={2014}
}
Nuclear receptors (NRs) are important pharmaceutical targets because they are key regulators of many metabolic and inflammatory diseases, including diabetes, dyslipidemia, cirrhosis, and fibrosis. As ligands play a pivotal role in modulating nuclear receptor activity, the discovery of novel ligands for nuclear receptors represents an interesting and promising therapeutic approach. The search for novel NR agonists and antagonists with enhanced selectivities prompted the exploration of the… CONTINUE READING

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