Targeting Mitochondria to Counteract Age-Related Cellular Dysfunction

Abstract

Senescence is related to the loss of cellular homeostasis and functions, which leads to a progressive decline in physiological ability and to aging-associated diseases. Since mitochondria are essential to energy supply, cell differentiation, cell cycle control, intracellular signaling and Ca2+ sequestration, fine-tuning mitochondrial activity appropriately… (More)
DOI: 10.3390/genes9030165

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