Targeting Integrin α4β7 in Steroid-Refractory Intestinal Graft-versus-Host Disease.

@article{Flisand2017TargetingI,
  title={Targeting Integrin α4β7 in Steroid-Refractory Intestinal Graft-versus-Host Disease.},
  author={Yngvar Fl\oisand and Knut E. A. Lundin and Vladimir Lj Lazarevic and J\orn Kristiansen and Liv Toril Osnes and Geir Erland Tj\onnfjord and Henrik Mikael Reims and Tobias Gedde-Dahl},
  journal={Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation},
  year={2017},
  volume={23 1},
  pages={172-175}
}
Steroid refractory acute graft-versus-host-disease of the gut is a serious complication associated with high mortality after allogeneic stem cell transplantation. Treatment options are limited and not predictably effective. We describe the treatment of steroid-refractory acute graft-versus-host-disease with vedolizumab, an antibody directed against integrin… CONTINUE READING