Targeting IL-6 receptor in the treatment of neuromyelitis optica spectrum: a review of emerging treatment options

@article{Rosso2020TargetingIR,
  title={Targeting IL-6 receptor in the treatment of neuromyelitis optica spectrum: a review of emerging treatment options},
  author={Mattia Rosso and Shrishti Saxena and Tanuja Chitnis},
  journal={Expert Review of Neurotherapeutics},
  year={2020},
  volume={20},
  pages={509 - 516}
}
ABSTRACT Introduction: Recent research has shown that IL-6 receptor (IL-6 R) inhibitors like tocilizumab and satralizumab are effective in reducing the relapse rate in patients with NMOSD. Areas covered: This review article explores current concepts in NMOSD management and focuses on IL-6 R as a therapeutic target. The authors delve into the biological and immunological role of IL-6 in the pathogenesis of NMOSD. Further, the authors summarize the most recent findings on the use of anti-IL-6 R… Expand
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