Targeting Human Cancer Xenografts with Monoclonal Antibodies Labeled Using Radioiodinated , Diethylenetriaminepentaacetic Acid-appended Peptides

@inproceedings{2007TargetingHC,
  title={Targeting Human Cancer Xenografts with Monoclonal Antibodies Labeled Using Radioiodinated , Diethylenetriaminepentaacetic Acid-appended Peptides},
  author={},
  year={2007}
}
  • Published 2007
A new nonmetabolizable peptide approach to the production of residualizing radioiodine was evaluated in nude mice bearing xenografts of human lung adenocarcinoma (Calu-3) and B-cell lymphoma (Ramos). Monoclonal antibodies (MAbs) RS7 (anti-epithelial glycoprotein-1) and LL2 (anti-CD22) were radioiodinated using the thiol-reactive diethylenetriaminepentaacet… CONTINUE READING