Targeting Glioblastoma with the Use of Phytocompounds and Nanoparticles

  title={Targeting Glioblastoma with the Use of Phytocompounds and Nanoparticles},
  author={Francesca Pistollato and Susanne Bremer-Hoffmann and Giuseppe Basso and Sandra Sumalla Cano and I{\~n}aki El{\'i}o and Manuel Masias Vergara and Francesca Giampieri and Maurizio Battino},
  journal={Targeted Oncology},
Glioblastoma multiforme (GBM) are extremely lethal and still poorly treated primary brain tumors, characterized by the presence of highly tumorigenic cancer stem cell (CSC) subpopulations, considered responsible for tumor relapse. In order to successfully eradicate GBM growth and recurrence, new anti-cancer strategies selectively targeting CSCs should be designed. CSCs might be eradicated by targeting some of their cell surface markers and transporters, inducing their differentiation, impacting… CONTINUE READING