Targeting E3 ubiquitin ligases for cancer therapy.

  • Yi Sun
  • Published 2003 in Cancer biology & therapy


E3 ubiquitin ligases are a large family of proteins that can be classified into three major structurally distinct types: N-end rule E3s, E3s containing the HECT (Homology to E6AP C-Terminus) domain, and E3s with the RING (Really Interesting New Gene) finger, including its derivatives, the U- Box and the PHD (Plant Homeo-Domain). E3 ubiquitin ligases exist… (More)


Cite this paper

@article{Sun2003TargetingEU, title={Targeting E3 ubiquitin ligases for cancer therapy.}, author={Yi Sun}, journal={Cancer biology & therapy}, year={2003}, volume={2 6}, pages={623-9} }