Targeting B Cells and Plasma Cells in Autoimmune Diseases

Abstract

Success with B cell depletion using rituximab has proven the concept that B lineage cells represent a valid target for the treatment of autoimmune diseases, and has promoted the development of other B cell targeting agents. Present data confirm that B cell depletion is beneficial in various autoimmune disorders and also show that it can worsen the disease… (More)
DOI: 10.3389/fimmu.2018.00835

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