Targeted ultra-deep sequencing reveals recurrent and mutually exclusive mutations of cancer genes in blastic plasmacytoid dendritic cell neoplasm

Abstract

Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare haematopoietic malignancy characterized by dismal prognosis and overall poor therapeutic response. Since the biology of BPDCN is barely understood, our study aims to shed light on the genetic make-up of these highly malignant tumors. Using targeted high-coverage massive parallel sequencing, we… (More)

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@inproceedings{Stenzinger2014TargetedUS, title={Targeted ultra-deep sequencing reveals recurrent and mutually exclusive mutations of cancer genes in blastic plasmacytoid dendritic cell neoplasm}, author={Albrecht Stenzinger and Volker Endris and Nicole Pfarr and Mindaugas Andrulis and Korinna J{\"{o}hrens and Frederick Klauschen and Udo Siebolts and Thomas Wolf and Philipp-Sebastian Koch and Miriam Schulz and Wolfgang Hartschuh and Sergij Goerdt and Jochen K Lennerz and Claudia Wickenhauser and Wolfram Klapper and Ioannis Anagnostopoulos and Wilko Weichert}, booktitle={Oncotarget}, year={2014} }