Targeted transduction patterns in the mouse brain by lentivirus vectors pseudotyped with VSV, Ebola, Mokola, LCMV, or MuLV envelope proteins.

@article{Watson2002TargetedTP,
  title={Targeted transduction patterns in the mouse brain by lentivirus vectors pseudotyped with VSV, Ebola, Mokola, LCMV, or MuLV envelope proteins.},
  author={Deborah J. Watson and Gary P Kobinger and Marco A. Passini and James Michael Wilson and John N H Wolfe},
  journal={Molecular therapy : the journal of the American Society of Gene Therapy},
  year={2002},
  volume={5 5 Pt 1},
  pages={528-37}
}
Lentiviral vectors have proven to be promising tools for transduction of central nervous system (CNS) cells in vivo and in vitro. In this study, CNS transduction patterns of lentiviral vectors pseudotyped with envelope glycoproteins from Ebola virus, murine leukemia virus (MuLV), lymphocytic choriomeningitis virus (LCMV), or the rabies-related Mokola virus were compared to a vector pseudotyped with the vesicular stomatitis virus glycoprotein (VSV-G). Mokola-, LCMV-, and VSV-G-pseudotyped… CONTINUE READING
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