Targeted therapy for the treatment of advanced non-small cell lung cancer: a review of the epidermal growth factor receptor antagonists.

@article{Silvestri2005TargetedTF,
  title={Targeted therapy for the treatment of advanced non-small cell lung cancer: a review of the epidermal growth factor receptor antagonists.},
  author={Gerard A. Silvestri and M Patricia Rivera},
  journal={Chest},
  year={2005},
  volume={128 6},
  pages={3975-84}
}
Lung cancer is the most common cause of cancer death. The vast majority of patients present with non-small cell lung cancer (NSCLC) in advanced inoperable stages. The current first-line treatment for patients with advanced NSCLC includes chemotherapy and palliative radiotherapy, but most patients relapse and eventually succumb to the disease. Advances in our knowledge of cancer cell biology have led to the development of specific molecular-targeted therapeutic agents. Mutations in the epidermal… CONTINUE READING

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References

Publications referenced by this paper.
Showing 1-10 of 69 references

Erlotinib in previously tested non - small cell lung cancer

D Cella, DT Eton, DL Fairclough
N Engl J Med • 2005

A phase II study

ES Kim, AM Mauer, HT Tran
Am Soc Clin Oncol • 2004

Activating mutations

TJ Lynch, DW Bell, R Sordella
apy. Proc Am Soc Clin Oncol • 2004

American Society of Clinical Oncology treatment of unresectable non-small-cell lung cancer guideline: update 2003.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology • 2004

CI-1033, a pan-erbB

WJ Slichenmyer, WL Elliott, DW. Fry
Oncol • 2004

Compassionate use

R Zinner, R Govindan, AJ Wozniak
Clin Oncol • 2004

EGF receptor gene

W Pao, V Miller, M Zakowski
Science • 2004

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