Targeted therapy for brain tumours

@article{Lesniak2004TargetedTF,
  title={Targeted therapy for brain tumours},
  author={Maciej S. Lesniak and Henry Brem},
  journal={Nature Reviews Drug Discovery},
  year={2004},
  volume={3},
  pages={499-508}
}
Although previously considered untreatable, brain tumours no longer carry the same prognosis as they did even a decade ago. Recent advances in drug delivery to the central nervous system have not only bypassed physiological constraints such as the blood–brain barrier, but have, in fact, changed the course of treatment for patients with malignant brain tumours. The creation of targeted therapies, which spare normal tissue and destroy tumour cells, is changing the field of neuro-oncology. In this… CONTINUE READING
52 Citations
106 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 52 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 106 references

a phase I/II study

  • Lidar, Z. et al. Convection-enhanced delivery of paclitaxel glioma
  • J. Neurosurg. 100, 472–479
  • 2004

A randomized, double-blind, placebocontrolled, phase 2 study of RMP-7 in combination with carboplatin administered intravenously for the treatment of recurrent malignant glioma

  • Prados, D M.
  • Neuro-oncology
  • 2003

Similar Papers

Loading similar papers…