Targeted therapies for systemic sclerosis

  title={Targeted therapies for systemic sclerosis},
  author={Christopher P. Denton and Voon Ong},
  journal={Nature Reviews Rheumatology},
Pathogenic processes that underlie the development and progression of systemic sclerosis (SSc) are being defined in preclinical, clinical and genetic studies. Important evidence of interplay between the vasculature, connective tissue and specialized epithelial structures is emerging, and abnormalities of both the innate and adaptive immune systems have been… CONTINUE READING