Targeted temperature management at 33°C versus 36°C after cardiac arrest.

@article{Nielsen2013TargetedTM,
  title={Targeted temperature management at 33°C versus 36°C after cardiac arrest.},
  author={Niklas Gonlund Nielsen and J{\o}rn Wetterslev and Tobias Cronberg and David Erlinge and Y. H. Gasche and Christian Hassager and Janneke Horn and Jan Hovdenes and Jesper Kjaergaard and Michael A. Kuiper and Tommaso Pellis and Pascal Stammet and Michael C Jaeger Wanscher and Matt P Wise and Anders Aneman and N Al-subaie and S{\o}ren Boesgaard and Mark{\'e}ta Kře{\vc}kov{\'a} and Iole Brunetti and Jan Frederik Bugge and Christopher D Hingston and Nicole P Juffermans and Matty Koopmans and Lars Valeur K{\o}ber and J{\o}rund Lang{\o}rgen and Gisela Lilja and Jacob Eifer M{\o}ller and Malin Rundgren and Christian Rylander and Ondřej {\vS}m{\'i}d and Christophe Werer and Per Winkel and Hans Henrik Friberg},
  journal={The New England journal of medicine},
  year={2013},
  volume={369 23},
  pages={
          2197-206
        }
}
BACKGROUND Unconscious survivors of out-of-hospital cardiac arrest have a high risk of death or poor neurologic function. Therapeutic hypothermia is recommended by international guidelines, but the supporting evidence is limited, and the target temperature associated with the best outcome is unknown. Our objective was to compare two target temperatures, both intended to prevent fever. METHODS In an international trial, we randomly assigned 950 unconscious adults after out-of-hospital cardiac… CONTINUE READING

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