Targeted protein unfolding uncovers a Golgi-specific transcriptional stress response

@inproceedings{Serebrenik2018TargetedPU,
  title={Targeted protein unfolding uncovers a Golgi-specific transcriptional stress response},
  author={Yevgeniy V. Serebrenik and Doris Hellerschmied and Momar Gaya Toure and Francesc L{\'o}pez-Gir{\'a}ldez and Dennis Brookner and Craig M Crews},
  booktitle={Molecular biology of the cell},
  year={2018}
}
In eukaryotic cells, organelle-specific stress-response mechanisms are vital for maintaining cellular homeostasis. The Golgi apparatus, an essential organelle of the secretory system, is the major site of protein modification and sorting within a cell and functions as a platform for spatially regulated signaling. Golgi homeostasis mechanisms that regulate organelle structure and ensure precise processing and localization of protein substrates remain poorly understood. Using a chemical biology… CONTINUE READING
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References

Publications referenced by this paper.
SHOWING 1-10 OF 63 REFERENCES

Identification of hydrophobic tags for the degradation of stabilized proteins.

  • Chembiochem : a European journal of chemical biology
  • 2012
VIEW 11 EXCERPTS
HIGHLY INFLUENTIAL

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