Targeted protein unfolding uncovers a Golgi-specific transcriptional stress response

@article{Serebrenik2018TargetedPU,
  title={Targeted protein unfolding uncovers a Golgi-specific transcriptional stress response},
  author={Yevgeniy V. Serebrenik and D. Hellerschmied and M. Toure and F. L{\'o}pez-Gir{\'a}ldez and D. Brookner and C. Crews},
  journal={Molecular Biology of the Cell},
  year={2018},
  volume={29},
  pages={1284 - 1298}
}
In eukaryotic cells, organelle-specific stress-response mechanisms are vital for maintaining cellular homeostasis. The Golgi apparatus, an essential organelle of the secretory system, is the major site of protein modification and sorting within a cell and functions as a platform for spatially regulated signaling. Golgi homeostasis mechanisms that regulate organelle structure and ensure precise processing and localization of protein substrates remain poorly understood. Using a chemical biology… Expand
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