Targeted neurotechnology restores walking in humans with spinal cord injury

@article{Wagner2018TargetedNR,
  title={Targeted neurotechnology restores walking in humans with spinal cord injury},
  author={Fabien B. Wagner and Jean-Baptiste Mignardot and Camille G Le Goff-Mignardot and Robin Demesmaeker and Salif Komi and Marco Capogrosso and Andreas Rowald and Ismael Se{\'a}{\~n}ez and Miroslav Caban and Elvira Pirondini and Molywan Vat and Laura A. McCracken and Roman Heimgartner and Isabelle Fodor and Anne Watrin and Perrine S{\'e}guin and Edoardo Paoles and Katrien Keybus and Gr{\'e}goire Eberle and Brigitte Schurch and Etienne Pralong and Fabio Becce and John O. Prior and Nicholas Buse and Rik Buschman and Esra Neufeld and Niels Kuster and Stefano Carda and Joachim von Zitzewitz and Vincent Delattre and Tim Denison and Hendrik Lambert and Karen Minassian and Jocelyne Bloch and Gr{\'e}goire Courtine},
  journal={Nature},
  year={2018},
  volume={563},
  pages={65-71}
}
Spinal cord injury leads to severe locomotor deficits or even complete leg paralysis. Here we introduce targeted spinal cord stimulation neurotechnologies that enabled voluntary control of walking in individuals who had sustained a spinal cord injury more than four years ago and presented with permanent motor deficits or complete paralysis despite extensive rehabilitation. Using an implanted pulse generator with real-time triggering capabilities, we delivered trains of spatially selective… 

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