Targeted mutagenesis tools for modelling psychiatric disorders

  title={Targeted mutagenesis tools for modelling psychiatric disorders},
  author={Jan M. Deussing},
  journal={Cell and Tissue Research},
In the 1980s, the basic principles of gene targeting were discovered and forged into sharp tools for efficient and precise engineering of the mouse genome. Since then, genetic mouse models have substantially contributed to our understanding of major neurobiological concepts and are of utmost importance for our comprehension of neuropsychiatric disorders… CONTINUE READING