Targeted monitoring of donor-specific HLA antibodies following renal transplantation.

@article{Almeshari2011TargetedMO,
  title={Targeted monitoring of donor-specific HLA antibodies following renal transplantation.},
  author={Khalid Almeshari and Alida P{\'a}ll and Ahmed Chaballout and Hazem Abdellah Shaaban Elgamal and Hadeel Almana and Fadi Alzayer and Nawaf Abaalkhail and Mai Altalhi},
  journal={Clinical transplants},
  year={2011},
  pages={
          395-400
        }
}
Development of de novo donor-specific anti-HLA antibody (DSA) with antibody-mediated rejection (AMR) is the most important cause of renal allograft loss. Therefore, DSA monitoring might identify grafts susceptible to chronic humoral injury. However, implementing universal monitoring is logistically difficult, costly, and not yet supported by management guidelines, especially in patients with stable graft function. To gain further insight into humoral alloimmunity in transplant patients, we… CONTINUE READING

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