Targeted metabolomics for biomarker discovery.

  title={Targeted metabolomics for biomarker discovery.},
  author={W. Griffiths and T. Koal and Yuqin Wang and M. Kohl and D. Enot and H. Deigner},
  journal={Angewandte Chemie},
  volume={49 32},
  • W. Griffiths, T. Koal, +3 authors H. Deigner
  • Published 2010
  • Computer Science, Medicine
  • Angewandte Chemie
  • Metabolomics is a truly interdisciplinary field of science, which combines analytical chemistry, platform technology, mass spectrometry, and NMR spectroscopy with sophisticated data analysis. Applied to biomarker discovery, it includes aspects of pathobiochemistry, systems biology/medicine, and molecular diagnostics and requires bioinformatics and multivariate statistics. While successfully established in the screening of inborn errors in neonates, metabolomics is now widely used in the… CONTINUE READING
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