Targeted metabolomics for biomarker discovery.

@article{Griffiths2010TargetedMF,
  title={Targeted metabolomics for biomarker discovery.},
  author={W. Griffiths and T. Koal and Yuqin Wang and M. Kohl and D. Enot and H. Deigner},
  journal={Angewandte Chemie},
  year={2010},
  volume={49 32},
  pages={
          5426-45
        }
}
  • W. Griffiths, T. Koal, +3 authors H. Deigner
  • Published 2010
  • Computer Science, Medicine
  • Angewandte Chemie
  • Metabolomics is a truly interdisciplinary field of science, which combines analytical chemistry, platform technology, mass spectrometry, and NMR spectroscopy with sophisticated data analysis. Applied to biomarker discovery, it includes aspects of pathobiochemistry, systems biology/medicine, and molecular diagnostics and requires bioinformatics and multivariate statistics. While successfully established in the screening of inborn errors in neonates, metabolomics is now widely used in the… CONTINUE READING
    206 Citations
    Assay Tools for Metabolomics
    • 9
    New frontiers in metabolomics: from measurement to insight
    • 70
    Advances in mass spectrometry applied to pharmaceutical metabolomics
    • 49
    H-NMR-based metabolite profiling for biomarker identification.
    • 7
    LC-MS-based metabolomics.
    • 296
    Metabolomics in rheumatic diseases: desperately seeking biomarkers
    • 75

    References

    SHOWING 1-10 OF 175 REFERENCES
    Mass spectrometry-based metabolomics.
    • 1,523
    • PDF
    Application of metabolomics to cardiovascular biomarker and pathway discovery.
    • 204
    Clinical Applications of Metabolomics in Oncology: A Review
    • 578
    • PDF
    Mass spectrometry: from proteomics to metabolomics and lipidomics.
    • W. Griffiths, Yuqin Wang
    • Chemistry, Medicine
    • Chemical Society reviews
    • 2009
    • 217
    • PDF
    The Expanding Role of Mass Spectrometry in Metabolite Profiling and Characterization
    • 189
    • PDF
    Analytical and statistical approaches to metabolomics research.
    • 196
    Metabolomics and Metabolite Profiling: Past Heroes and Future Developments
    • 42
    • PDF