Targeted metabolomic analysis reveals the association between the postprandial change in palmitic acid, branched-chain amino acids and insulin resistance in young obese subjects.

@article{Liu2015TargetedMA,
  title={Targeted metabolomic analysis reveals the association between the postprandial change in palmitic acid, branched-chain amino acids and insulin resistance in young obese subjects.},
  author={Liyan Liu and Rennan Feng and Fuchuan Guo and Ying Li and J. Jiao and Changhao Sun},
  journal={Diabetes research and clinical practice},
  year={2015},
  volume={108 1},
  pages={
          84-93
        }
}
Obesity is the result of a positive energy balance and often leads to difficulties in maintaining normal postprandial metabolism. The changes in postprandial metabolites after an oral glucose tolerance test (OGTT) in young obese Chinese men are unclear. In this work, the aim is to investigate the complex metabolic alterations in obesity provoked by an OGTT using targeted metabolomics. We used gas chromatography-mass spectrometry and ultra high performance liquid chromatography-triple quadrupole… CONTINUE READING
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