Targeted lymph node immunization can protect cats from a mucosal challenge with feline immunodeficiency virus.

@article{Finerty2001TargetedLN,
  title={Targeted lymph node immunization can protect cats from a mucosal challenge with feline immunodeficiency virus.},
  author={Suzan Finerty and Christopher Richard Stokes and Timothy John Gruffydd-Jones and Tim J Hillman and Frances Jenifer Barr and David A. Harbour},
  journal={Vaccine},
  year={2001},
  volume={20 1-2},
  pages={
          49-58
        }
}
With the rapid spread of human immunodeficiency virus (HIV) infection worldwide it is clear that effective strategies for mucosal vaccination against lentiviruses are urgently required. The aim of the present study is to determine whether protective immune responses against a mucosal challenge by feline immunodeficiency virus (FIV) can be elicited by targeting the immunization to the medial iliac lymph nodes--the principal site of migration of cells from the genital and rectal mucosa. Cats were… CONTINUE READING
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