Targeted liposome-loaded microbubbles for cell-specific ultrasound-triggered drug delivery.


One of the main problems in cancer treatment is disease relapse through metastatic colonization, which is caused by circulating tumor cells (CTCs). This work reports on liposome-loaded microbubbles targeted to N-cadherin, a cell-cell adhesion molecule expressed by CTCs. It is shown that such microbubbles can indeed bind to N-cadherin at the surface of HMB2… (More)
DOI: 10.1002/smll.201300161

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