Targeted liposome-loaded microbubbles for cell-specific ultrasound-triggered drug delivery.

Abstract

One of the main problems in cancer treatment is disease relapse through metastatic colonization, which is caused by circulating tumor cells (CTCs). This work reports on liposome-loaded microbubbles targeted to N-cadherin, a cell-cell adhesion molecule expressed by CTCs. It is shown that such microbubbles can indeed bind to N-cadherin at the surface of HMB2… (More)
DOI: 10.1002/smll.201300161

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