Targeted inactivation of the gene encoding the mouse alpha 2c-adrenoceptor homolog.

Abstract

alpha 2-Adrenergic receptors (alpha 2-ARs) regulate a wide range of physiological functions and are targets for clinically important antihypertensive and anesthetic agents. Three genes encoding alpha 2-AR subtypes have been cloned in humans and mice, but the physiological significance of each subtype has not been completely characterized. The available… (More)

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@article{Link1995TargetedIO, title={Targeted inactivation of the gene encoding the mouse alpha 2c-adrenoceptor homolog.}, author={Richard E. Link and Maryjane Stevens and M Kulatunga and Martin Scheinin and Gregory S Barsh and Brian K. Kobilka}, journal={Molecular pharmacology}, year={1995}, volume={48 1}, pages={48-55} }