Targeted epidermal growth factor receptor nanoparticle bioconjugates for breast cancer therapy.

@article{Acharya2009TargetedEG,
  title={Targeted epidermal growth factor receptor nanoparticle bioconjugates for breast cancer therapy.},
  author={Sarbari Acharya and Fahima Dilnawaz and Sanjeeb Kumar Sahoo},
  journal={Biomaterials},
  year={2009},
  volume={30 29},
  pages={5737-50}
}
Selective drug delivery is an important approach with great potential for overcoming problems associated with the systemic toxicity and poor bioavailability of antineoplastic drugs. Nanomedicine plays a pivotal role by delivering drugs in a targeted manner to the malignant tumor cells thereby reducing the systemic toxicity of the anticancer drugs. The objective of this study was to prepare and characterize rapamycin loaded polymeric poly(lactide-co-glycolide) (PLGA) nanoparticles (NP) that were… CONTINUE READING

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