Targeted disruption of Noc4l leads to preimplantation embryonic lethality in mice

Abstract

Human Nucleolar complex associated 4 homolog (NOC4L, GenBank accession number NM_024078) is the human ortholog of yeast Noc4p. However, with few functional studies evaluated, the physiological contributions of NOC4L have yet to be defined. The Noc4p gene in yeast encodes a 63-kilodalton (KDa) protein that forms a stable heterodimer with Nop14p, which… (More)
DOI: 10.1007/s13238-016-0335-9

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