Targeted and exome sequencing identified somatic mutations in hepatocellular carcinoma.

Abstract

AIM Genetic analysis has revealed a subset of recurrently mutated genes and aberrant cellular signaling pathways in hepatocellular carcinoma. To investigate genetic alterations and dysregulated pathways in hepatocellular carcinoma, we performed targeted sequencing and exome analysis using next-generation sequencer. METHODS We analyzed the somatic… (More)
DOI: 10.1111/hepr.12663

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Cite this paper

@article{Hirotsu2016TargetedAE, title={Targeted and exome sequencing identified somatic mutations in hepatocellular carcinoma.}, author={Yosuke Hirotsu and Tang-Hui Zheng and Kenji Amemiya and Hitoshi Mochizuki and Bayasi Guleng and Masao Omata}, journal={Hepatology research : the official journal of the Japan Society of Hepatology}, year={2016}, volume={46 11}, pages={1145-1151} }