Targeted accumulation of polyethylene glycol-coated immunoliposomes in infarcted rabbit myocardium.

Abstract

The less than optimal accumulation of immunoliposome-associated reagents at target sites has often been attributed to the rapid in vivo clearance of immunoliposomes from the blood. In an attempt to overcome the drawback of rapid clearance and use the targeting potential of immunoliposomes, we have prepared long-circulating, 111In-labeled immunoliposomes… (More)

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@article{Torchilin1992TargetedAO, title={Targeted accumulation of polyethylene glycol-coated immunoliposomes in infarcted rabbit myocardium.}, author={Vladimir Torchilin and A. L. Klibanov and L. Huang and Sharon I O'Donnell and N D Nossiff and Ban An Khaw}, journal={FASEB journal : official publication of the Federation of American Societies for Experimental Biology}, year={1992}, volume={6 9}, pages={2716-9} }