Targeted Retrieval and Analysis of Five Neandertal mtDNA Genomes

@article{Briggs2009TargetedRA,
  title={Targeted Retrieval and Analysis of Five Neandertal mtDNA Genomes},
  author={Adrian W. Briggs and J. M. Good and R. Green and J. Krause and T. Maricic and U. Stenzel and C. Lalueza-Fox and P. Rudan and D. Brajkovi{\'c} and Željko Ku{\'c}an and I. Gu{\vs}i{\'c} and R. Schmitz and V. Doronichev and L. Golovanova and M. de la Rasilla and J. Fortea and A. Rosas and S. P{\"a}{\"a}bo},
  journal={Science},
  year={2009},
  volume={325},
  pages={318 - 321}
}
Economic Ancient DNA Sequencing Analysis of ancient DNA is often limited by the availability of ancient material for sequencing. Briggs et al. (p. 318; see the news story by Pennisi) describe a method of ancient DNA sequence retrieval that greatly reduces shotgun sequencing costs while avoiding the many difficulties associated with direct PCR-based approaches. They generated five complete and one near-complete Neandertal mitochondrial DNA genomes, which would have been economically impossible… Expand
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