Corpus ID: 116098541

Targeted Polymeric Nanoparticles: Radiolabelling with GA-67 and in vivo evaluation in a mouse model of pancreatic adenocarcinoma using single photon emission computerized tomography

@inproceedings{Iceta2016TargetedPN,
  title={Targeted Polymeric Nanoparticles: Radiolabelling with GA-67 and in vivo evaluation in a mouse model of pancreatic adenocarcinoma using single photon emission computerized tomography},
  author={L. Iceta},
  year={2016}
}
Nanoparticle (NP) based theranostics may play a pivotal role in oncology in the near future. However, determination of the pharmacokinetic (PK) properties of novel nanomedicines, which is essential for the determination of the effective dose and potential translation into the clinical setting, is extremely challenging. Radiolabelling of the NPs with positron or gamma emitters and subsequent imaging studies using nuclear imaging techniques can provide relevant information on the PK properties of… Expand

References

SHOWING 1-10 OF 23 REFERENCES
Long-term multimodal imaging of tumor draining sentinel lymph nodes using mesoporous silica-based nanoprobes.
  • 102
Fundamentals of Positron Emission Tomography and Applications in Preclinical Drug Development
  • S. Cherry
  • Medicine
  • Journal of clinical pharmacology
  • 2001
  • 139
Factors controlling nanoparticle pharmacokinetics: an integrated analysis and perspective.
  • 361
  • Highly Influential
Formulation of functionalized PLGA-PEG nanoparticles for in vivo targeted drug delivery.
  • 1,027
  • PDF
Recent advances in iron oxide nanocrystal technology for medical imaging.
  • 1,254
Long-circulating and target-specific nanoparticles: theory to practice.
  • 3,091
  • PDF
Automated production of copper radioisotopes and preparation of high specific activity [(64)Cu]Cu-ATSM for PET studies.
  • M. Matarrese, P. Bedeschi, +8 authors F. Fazio
  • Chemistry, Medicine
  • Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine
  • 2010
  • 37
...
1
2
3
...