Targeted Gene Disruption by Ectopic Induction of DNA Elimination in Tetrahymena.


Tetrahymena is a useful eukaryotic model for biochemistry and molecular cell biology studies. We previously demonstrated that targeted ectopic DNA elimination, also called co-Deletion (coDel), can be induced by the introduction of an internal eliminated sequence (IES)-target DNA chimeric construct. In this study, we demonstrate that coDel occurs at most of… (More)
DOI: 10.1534/genetics.115.178525


7 Figures and Tables

Blog articles referencing this paper

  • New in GENETICS!

    Genes to Genomes · Sep 09, 2015

  • Don't see an article that should be here?

Slides referencing similar topics