Targeted Enrichment: Maximizing Orthologous Gene Comparisons across Deep Evolutionary Time

  title={Targeted Enrichment: Maximizing Orthologous Gene Comparisons across Deep Evolutionary Time},
  author={Shannon M. Hedtke and Matthew J. Morgan and David C Cannatella and David M. Hillis},
  booktitle={PloS one},
Estimated phylogenies of evolutionarily diverse taxa will be well supported and more likely to be historically accurate when the analysis contains large amounts of data-many genes sequenced across many taxa. Inferring such phylogenies for non-model organisms is challenging given limited resources for whole-genome sequencing. We take advantage of genomic data from a single species to test the limits of hybridization-based enrichment of hundreds of exons across frog species that diverged up to… CONTINUE READING
Highly Cited
This paper has 59 citations. REVIEW CITATIONS

From This Paper

Figures, tables, and topics from this paper.


Publications citing this paper.
Showing 1-10 of 31 extracted citations

Targeted capture in evolutionary and ecological genomics.

Molecular ecology • 2016
View 9 Excerpts
Highly Influenced

60 Citations

Citations per Year
Semantic Scholar estimates that this publication has 60 citations based on the available data.

See our FAQ for additional information.


Publications referenced by this paper.
Showing 1-10 of 53 references

NimbleGen Array User’s Guide: Titanium Optimized Sequence Capture v1.0

Roche NimbleGen, Inc
Madison: Roche NimbleGen, • 2009
View 3 Excerpts
Highly Influenced

Global patterns of diversification in the history of modern amphibians.

Proceedings of the National Academy of Sciences of the United States of America • 2007
View 7 Excerpts
Highly Influenced

The major clades of frogs

LS Ford, DC Cannatella
Herpetol Monogr • 1993
View 8 Excerpts
Highly Influenced

A new look at the statistical model identification

H Akaike
IEEE T Automat Contr • 1974
View 2 Excerpts
Highly Influenced

The pipid root

S Hoegg, M Vences, H Brinkmann, A Meyer
Syst Biol • 2012

Similar Papers

Loading similar papers…