Targeted Acid-Sensing Ion Channel Therapies for Migraine

Abstract

Acid-sensing ion channels (ASICs) are a family of ion channels, consisting of four members; ASIC1 to 4. These channels are sensitive to changes in pH and are expressed throughout the central and peripheral nervous systems—including brain, spinal cord, and sensory ganglia. They have been implicated in a number of neurological conditions such as stroke and… (More)
DOI: 10.1007/s13311-018-0619-2

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