TargetRNA: a tool for predicting targets of small RNA action in bacteria

  title={TargetRNA: a tool for predicting targets of small RNA action in bacteria},
  author={Brian Tjaden},
  booktitle={Nucleic Acids Research},
Many small RNA (sRNA) genes in bacteria act as posttranscriptional regulators of target messenger RNAs. Here, we present TargetRNA, a web tool for predicting mRNA targets of sRNA action in bacteria. TargetRNA takes as input a genomic sequence that may correspond to an sRNA gene. TargetRNA then uses a dynamic programming algorithm to search each annotated message in a specified genome for mRNAs that evince basepair-binding potential to the input sRNA sequence. Based on the calculated basepair… CONTINUE READING
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