Target of rapamycin-dependent activation of S6 kinase is a central step in the transduction of nutritional signals during egg development in a mosquito.

@article{Hansen2005TargetOR,
  title={Target of rapamycin-dependent activation of S6 kinase is a central step in the transduction of nutritional signals during egg development in a mosquito.},
  author={Immo Alex Hansen and Geoffrey M Attardo and Saurabh Ghosh Roy and Alexander S. Raikhel},
  journal={The Journal of biological chemistry},
  year={2005},
  volume={280 21},
  pages={20565-72}
}
Female mosquitoes are effective disease vectors, because they take blood from vertebrate hosts to obtain nutrients for egg development. Amino acid signaling via the target of rapamycin (TOR) pathway has been identified as a key requirement for the activation of egg development after a blood meal. We report the characterization of the TOR kinase and one of its major downstream targets, S6 kinase, of the yellow fever mosquito Aedes aegypti during egg development in adult females. Both TOR and S6K… CONTINUE READING

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