Target identification for biologically active small molecules using chemical biology approaches

  title={Target identification for biologically active small molecules using chemical biology approaches},
  author={Heesu Lee and Jae Wook Lee},
  journal={Archives of Pharmacal Research},
  • Heesu Lee, J. Lee
  • Published 8 July 2016
  • Biology, Medicine
  • Archives of Pharmacal Research
The identification and validation of the targets of biologically active molecules is an important step in the field of chemical biology. While recent advances in proteomic and genomic technology have accelerated this identification process, the discovery of small molecule targets remains the most challenging step. A general method for the identification of these small molecule targets has not yet been established. To overcome the difficulty in target identification, new technology derived from… Expand

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