Target cells in internal dosimetry.

  title={Target cells in internal dosimetry.},
  author={Wolfgang Goessner},
  journal={Radiation protection dosimetry},
  volume={105 1-4},
Data related to radium induced bone sarcomas in humans are used as a method of defining target cells on bone surfaces and in the bone marrow. The differential distribution of radiation induced bone sarcoma types, with a high ratio of non-bone producing, mainly fibroblastic tumours, challenges the ICRP concept that the bone lining cells are target cells. Multipotential mesenchymal stem cells are located within the range of alpha particles and are the most likely target cells for the fibroblastic… CONTINUE READING