Target binding improves relaxivity in aptamer–gadolinium conjugates


MRI contrast agents (CA) have been heavily used over the past several decades to enhance the diagnostic value of the obtained images. From a design perspective, two avenues to improve the efficacy of contrast agents are readily evident: optimization of magnetic properties of the CA, and optimization of the pharmacokinetics and distribution of the CA in the… (More)
DOI: 10.1007/s00775-012-0930-z

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