Target areas innervated by PACAP-immunoreactive retinal ganglion cells

@article{Hannibal2004TargetAI,
  title={Target areas innervated by PACAP-immunoreactive retinal ganglion cells},
  author={Jens Hannibal and Jan Fahrenkrug},
  journal={Cell and Tissue Research},
  year={2004},
  volume={316},
  pages={99-113}
}
The retinohypothalamic tract (RHT) originates from a subset of retinal ganglion cells (RGCs). The cells of the RHT co-store the neurotransmitters PACAP and glutamate, which in a complex interplay mediate light information to the circadian clock located in the suprachiasmatic nuclei (SCN). These ganglion cells are intrinsically photosensitive probably due to expression of melanopsin, a putative photoreceptor involved in light entrainment. In the present study we examined PACAP-containing retinal… CONTINUE READING
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