Target apex-seeking in factor analysis of medical image sequences.

@article{Buvat1993TargetAI,
  title={Target apex-seeking in factor analysis of medical image sequences.},
  author={Ir{\`e}ne Buvat and Habib Benali and Fr{\'e}d{\'e}rique Frouin and J. P. Bazin and Robert Di Paola},
  journal={Physics in medicine and biology},
  year={1993},
  volume={38 1},
  pages={
          123-38
        }
}
The aim of factor analysis of medical image sequences (FAMIS) is to estimate a limited number of physical or physiological fundamental functions. Its oblique rotation stage strongly affects the quality and the interpretation of the resulting estimates (factors and factor images). A new target apex-seeking method which integrates physical or physiological knowledge in this stage is described. This knowledge concerns some of the fundamental functions and reacts on the determination of all the… 

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References

SHOWING 1-10 OF 44 REFERENCES
Factor Analysis of Medical Image Sequences (FAMIS): Fundamental principles and applications
Factor Analysis of Medical Image Sequences aims at resolving a medical image sequences into its underlying fundamental functions and their associated fundamental spatial distributions, yielding a
Image Sequence Processing Using Factor Analysis And Compartmental Modelling
TLDR
This paper proposes an original way of introducing constraints, which is based on the a priori knowledge of the physiological data, and is applied to the study of 99mTc HMDP early kinetics in osseous tissues.
The effect of apex-finding errors on factor images obtained from factor analysis and oblique transformation.
  • A. Houston
  • Mathematics
    Physics in medicine and biology
  • 1984
TLDR
The effects of errors in apex-finding on physiological factors from a factor analysis of dynamic studies are investigated and it is shown that, apart from scaling, the factor image obtained from a given apex is independent of the position of that apex.
Handling of Dynamic Sequences in Nuclear Medicine
TLDR
The authors indicate what could be the flow chart of the processing of dynamic sequences in scintigraphy and the kind of material that would be necessary to implement it.
Factor analysis of dynamic function studies using a priori physiological information.
TLDR
A procedure called IBFADS (information-based factor analysis in dynamic structures) is described which incorporates the IM (intersection method) technique previously developed into FADS, in order to reduce the error in the estimation of the correct model.
The use of principal components in the quantitative analysis of gamma camera dynamic studies.
  • D. Barber
  • Biology
    Physics in medicine and biology
  • 1980
TLDR
Using a principal components analysis of the elemental curves representing the change of activity with time in each pixel, it is possible to extract the fundamental functional changes of activity which underly the observed variation of activity.
Background correction in factor analysis of dynamic scintigraphic studies: necessity and implementation.
TLDR
It is proved that the factor analysis method gives incorrect results when there is a total overlap of a structure, and by assuming a local homogeneity of the overlapping structure, the solution found can be greatly improved.
Introduction to holospectral imaging in nuclear medicine for scatter subtraction.
TLDR
An approach to image analysis and processing, called holospectral imaging, is proposed for dealing with Compton scattering contamination in nuclear medicine imaging, and results indicate a slight increase in the statistical noise but also an increase in contrast and greatly improved ability to quantitate the image.
A new vertex-finding algorithm for the oblique rotation step in factor analysis
TLDR
A new vertex-finding algorithm, based on an optimization of a function of the vertices, is investigated, which converges in the cases where the previous algorithm of Barber and Cavailloles diverges.
On the existence of an unambiguous solution in factor analysis of dynamic studies.
TLDR
This work has shown that the existence of physiologically related unique solution in factor analysis can be proved providing the number of factors is chosen properly.
...
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