Tardive dyskinesia is not associated with the polymorphisms of 5-HT2A receptor gene, serotonin transporter gene and catechol-o-methyltransferase gene.

@article{Herken2003TardiveDI,
  title={Tardive dyskinesia is not associated with the polymorphisms of 5-HT2A receptor gene, serotonin transporter gene and catechol-o-methyltransferase gene.},
  author={Hasan Herken and Mehmet Erdal and Omer B{\"o}ke and Haluk Asuman Savaş},
  journal={European psychiatry : the journal of the Association of European Psychiatrists},
  year={2003},
  volume={18 2},
  pages={77-81}
}
BACKGROUND The pathophysiology of tardive dyskinesia (TD) is not completely understood.Aim. - To assess the relationship of TD with 5-HT2A receptor gene, serotonin transporter gene (5 HTT), and catechol-o-methyltransferase (COMT) gene polymorphisms. METHOD Our study comprised 111 unrelated subjects who strictly met DSM-IV criteria for schizophrenia and 32 TD, and 79 healthy unrelated controls; all the subjects were of Turkish origin. The analyses of 5-HT2A receptor gene, 5 HTT gene, and COMT… CONTINUE READING